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| Product Name | Recombinant Human Single-strand selective monofunctional uracil DNA glycosylase |
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| Description | 1-177aa; Full Length of Isoform 2. MW: 35.61kD. Purity >90% as determined by SDS-PAGE. Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-h |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [single-strand selective monofunctional uracil DNA glycosylase isoform 1; Single-strand selective monofunctional uracil DNA glycosylase; single-strand-selective monofunctional uracil-DNA glycosylase 1] |
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| Gene, Accession, CAS # | SMUG1, Gene ID: 23583, Accession: NP_001230716.1 |
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| Catalog # | MBS1485178 |
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| Order / More Info | Recombinant Human Single-strand selective monofunctional uracil DNA glycosylase from MYBIOSOURCE INC. |
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| Product Specific References | Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors.Haushalter K.A., Stukenberg P.T., Kirschner M.W., Verdine G.L.Curr. Biol. 9:174-185(1999) Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions.Masaoka A., Matsubara M., Hasegawa R., Tanaka T., Kurisu S., Terato H., Ohyama Y., Karino N., Matsuda A., Ide H.Biochemistry 42:5003-5012(2003) Comple |
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