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| Product Name | ECSIT, 19-217aa, Human, His tag, E Coli |
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| Description | MW: 24.6 kDa (222aa) confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. ECSIT is a ubiquitously expressed protein that plays an important role as an adaptor protein in the cytosolic signal transduction cascade events triggered by Toll receptor activation. It was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Knockdown of ECSIT results in severely impaired complex I assembly and disturbed mitochondrial function |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Evolutionarily conserved signaling intermediate in Toll pathway mitochondrial; Evolutionarily conserved signaling intermediate in Toll pathway; mitochondrial; SITPEC] |
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| Gene, Accession, CAS # | ECSIT, Gene ID: 51295, Accession: NP_001135937 |
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| Catalog # | MBS204590 |
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| Order / More Info | ECSIT, 19-217aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Moustakas A., et al. (2003) Genes Dev17:2855-2859; Vogel R O., et al. (2007) Genes Dev. 21: 615-624. |
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