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| Product Name | ECSIT, Recombinant, Human, aa19-217, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). ECSIT is a ubiquitously expressed protein that plays an important role as an adaptor protein in the cytosolic signal transduction cascade events triggered by Toll receptor activation. It was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Knockdown of ECSIT results in severely impaired complex I assembly and disturbed mitochondrial function. Source: Recombinant protein corresponding to aa19-217 from human ECSIT at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~24.6kD (222aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGS VYYHILRADL LPPEEREVEE TPEEWNLYYP MQLDLEYVRS GWDNYEFDIN EVEEGPVFAM CMAGAHDQAT MAKWIQGLQE TNPTLAQIPV VFRLAGSTRE LQTSSAGLEE PPLPEDHQEE DDNLQRQQQG QS GTCGAAL TGTSISQVPL PKDSTGAADP PQPHIVGIQS PDQQAALARH NPARPVFVEG PFSLWLRNKC |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ECSIT, Recombinant, Human, aa19-217, His-Tag (Evolutionarily Conserved Signaling Intermediate in Toll Pathway Mitochondrial, SITPEC) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 138645 |
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| Order / More Info | ECSIT, Recombinant, Human, aa19-217, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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