| 产品详情 |
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| Antigenic Specificity | huntingtin (specific for expanded polyQ by western blot) |
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| Clone | MW1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | supernatant |
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| Size | 1.0 ml |
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| Concentration | n/a |
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| Applications | ELISA, FACS, Function Blocking, Immunofluorescence, Immunoprecipitation, Western Blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Epitope: N-terminal, polyQ. MW1 is specific for the elongated polyQ stretch through which mHtt aggregates. The epitope is hidden in aggregates. This antibody is also known as anti-polyQ. Appears to recognize an altered conformation of the polyQ domain generated as the polyQ domain of Htt increases in length. Time-resolved Foerster resonance energy transfer (TR-FRET) assay has been developed using MW1 to assay soluble huntingtin. PMID: 22365609 23966247 23626768 23100324 22984513. RRID:AB_528290 |
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| Immunogen | Recombinant DRPLA-19Q/GST fusion protein: Partial protein |
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| Other Names | HD, IT15 |
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| Gene, Accession # | HTT, Gene ID: 3064, UniProt: P42858 |
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| Catalog # | MW1 |
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| Price | |
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| Order / More Info | huntingtin (specific for expanded polyQ by western blot) Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK |
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| Product Specific References | PubMed: 11719267, 11719267, 19690053, 19491400, 22037470, 11719267, 24798518, 19491400, 20086007, 22919566, 26174131, 20086007, 11719267, 19491400, 26174131, 11792860 |
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