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| Product Name | L-733,060 hydrochloride |
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| Description | Potent NK1 antagonist (Ki values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors, respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze. Exhibits antitumor activity in vitro. Also decreases HER2 activity and tumor growth in mice bearing HER2+ or EGFR+ breast tumors. Orally bioavailable and brain penetrant. Purity 99%. MW (observed): 439.83 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S,3S)-3-[[3,5-bis(Trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine hydrochloride |
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| Gene, Accession, CAS # | CAS: 148687-76-7 |
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| Catalog # | 1145/50 |
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| Order / More Info | L-733,060 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 14617692, 17295025, 18337316, 18945947, 20720158, 22905134, 23345604, 23722916, 23996004, 26114632, 26363006, 28301610 |
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