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| Product Name | LZTFL1, 1-299aa, Human, His tag, E.coli |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In PBS buffer (pH 7.4) containing 10% glycerol, 1mM DTT. LZTFL1 is a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. LZTFL1 may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Recombinant human LZTFL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Leucine zipper transcription factor-like protein 1, Leucine zipper transcription factor-like protein 1, BBS17 |
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| Gene, Accession, CAS # | NP 065080 |
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| Catalog # | ATGP2929 |
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| Order / More Info | LZTFL1, 1-299aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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