| 产品详情 |
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| Product Name | Amphiregulin, Recombinant, Human (AR, AREG, Colorectum cell-derived growth factor (CRDGF)) |
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| Description | Purity ≥95% by SDS-PAGE gel and HPLC analyses. Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts.Amphiregulin also inhibits the growth of certain carcinoma cell lines.Synthesized as a transmembrane protein, Amphiregulinrsquos extracellular domain is proteolytically processed to release the mature protein.There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity.Recombinant human Amphiregulin is a 11.3kD glycoprotein consisting of 98 amino acid residues. Biological Activity: Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. The expected ED50 for this effect is 5-10ng/ml. AA Sequence: SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR KKKNPCNAEF QNFCIHGECK YIEHLEAVTC KCQQEYFGER CGEKSMKTHS MIDSSLSK Quality Control: Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143274 |
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| Order / More Info | Amphiregulin, Recombinant, Human (AR, AREG, Colorectum cell-derived growth factor (CRDGF)) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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