| 产品详情 |
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| Antigenic Specificity | serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | ELISA,Blocking Antibody (Inhibition),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Plasminogen Activator Inhibitor-1 (PAI-1, Serpin E1) is a member of the serpin family of serine protease inhibitors, and is the primary inhibitor of urokinase and tissue plasminogen activator (tPA). PAI-1 is expressed predominantly in adipose, liver and vascular tissues, and is also produced by certain tumor cells. Elevated levels of PAI-1 are associated with obesity, diabetes and cardiovascular disease, and increased production of PAI-1 is induced by various obesity related factors such as TNFa, glucose, insulin, and very-low-density lipoprotein. The obesity related elevation of PAI-1 levels along with the consequential deficiency in plasminogen activators can lead directly to increased risk of thrombosis and other coronary diseases. |
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| Immunogen | PAI1 antibody was raised in rabbit using highly pure recombinant human PAI-1 as the immunogen. |
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| Other Names | PAI|PAI-1|PAI1|PLANH1|si:ch211-138a11.1|SERPINE1|Planh1|B230326M24Rik|PI-7|PI7|PN-1|Spi4|HsT1201|PAI-2|PAI2|PLANH2|PAI1A|Pai1|Pai1aa|Planh|RATPAI1A |
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| Gene, Accession # | Gene ID: 5054 |
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| Catalog # | ABIN636679 |
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| Order / More Info | serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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