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Antigenic Specificity | serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 200 µg |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PAI1 is a member of the serpin family of serine protease inhibitors, and is the primary inhibitor of urokinase and tissue plasminogen activator (tPA). PAI-1 is expressed predominantly in adipose, liver and vascular tissues, and is also produced by certain tumor cells. Elevated levels of PAI-1 are associated with obesity, diabetes and cardiovascular disease, and increased production of PAI-1 is induced by various obesity related factors such as TNFa, glucose, insulin, and very-low-density lipoprotein. The obesity related elevation of PAI-1 levels along with the consequential deficiency in plasminogen activators can lead directly to increased risk of thrombosis and other coronary diseases. Synonyms: Polyclonal PAI1 antibody, Anti-PAI1 antibody, PAI-1 antibody, Plasminogen Activator Inhibitor-1 antibody, Serpin E1 antibody. |
Immunogen | PAI1 antibody (HRP) was raised in sheep using Recombinant Plasminogen Activator Inhibitor-1 prepared from bacterial extracts as the immunogen. |
Other Names | PAI|PAI-1|PAI1|PLANH1|si:ch211-138a11.1|SERPINE1|Planh1|B230326M24Rik|PI-7|PI7|PN-1|Spi4|HsT1201|PAI-2|PAI2|PLANH2|PAI1A|Pai1|Pai1aa|Planh|RATPAI1A |
Gene, Accession # | Gene ID: 5054 |
Catalog # | ABIN926404 |
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Order / More Info | serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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