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Product Name | Recombinant Human PDGFA Protein (Animal Free) |
Description | Purity >95% as determined by SDS-PAGE. Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b. |
Size | 2ug, 10ug, 100ug, 500ug, 1mg |
Concentration | n/a |
Applications | Bioactive |
Other Names | PDGF1, PDGF-A |
Gene, Accession, CAS # | PDGFA, Gene ID: 5154, UniProt: P04085 |
Catalog # | QP5294-2ug |
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Order / More Info | Recombinant Human PDGFA Protein (Animal Free) from ENQUIRE BIOREAGENTS |
Product Specific References | n/a |
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