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| Product Name | Dentin Matrix Protein 1, Recombinant, Mouse (DMP1) |
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| Description | Purity ≥ 85%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain.Endotoxin: ≤ 1EU/1ug. Dentin matrix protein 1 (DMP-1) is a member of the SIBLING family of proteins that includes bone sialoprotein, dentin sialophosphoprotein, MEPE, and osteopontin. These are highly phosphorylated integrin-binding proteins that are rich in acidic amino acids and function in the formation of calcified bone and tooth matrix (1, 2). Its phosphate content, spacing of acidic residues, and calcium-dependent dimerization of DMP-1 contribute to its ability to sequester calcium phosphate clusters and promote hydroxyapatite (HA) crystal formation (3-5). Mature mouse DMP-1 is 487 amino acids (aa) in length. It contains a poly-Pro segment (aa 41-44) and an RGD binding motif (aa 350-352). DMP-1 may be cleaved by BMP-1 family proteases at a single site which is conserved in human, generating a 37kD N-terminal (aa 17-212) and a 57kD C-terminal (aa 213-503) fragment (6). The N-terminal |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q2HJ09 |
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| Catalog # | D3154-75 |
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| Order / More Info | Dentin Matrix Protein 1, Recombinant, Mouse (DMP1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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