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| Product Name | Neurocan, Recombinant, Mouse |
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| Description | Purity ~95%, by SDS-PAGE under reducing conditions and visualized by silver stain (seen at 120-200kD, reducing conditions). Endotoxin: ≤0.1EU per 1ug (LAL). Mouse Neurocan is synthesized as a 1268 amino acid (aa) precursor that contains a 22aa signal sequence and a 1246aa mature chain. The mature chain contains one Iglike Vtype domain (aa37 157), two Link domains (aa159 254 and 258 356), two EGFlike domains (aa960 996 and 998 1034), one Ctype lectinlike domain (aa1036 1165), one Sushi domain (aa 1165 1224), and five potential sites for N-linked glycosylation. Mature mouse Neurocan is 90% and 66% aa identical to mature rat and human Neurocan, respectively. Neurocan binds with high affinity to the cell adhesion molecules (CAM) NgCAM and NCAM to inhibit Neuronal adhesion and neurite growth. In the developing rat retina, the expression of Neurocan is regulated both temporally and spatially, which suggests that it may play a role in the differentiation of and neural network formation of the |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P55066 |
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| Catalog # | N2137-04 |
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| Price | |
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| Order / More Info | Neurocan, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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