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Product Name | Recombinant Mouse IL-17AF Protein |
Description | Purity >95% as determined by SDS-PAGE. Interleukin 17AF (IL-17AF) is a heterodimer that is composed of the interleukin 17A (IL-17A) and interleukin 17F (IL-17F) members of the IL-17 family of cytokines. IL-17AF is produced by T helper 17 cells (Th17) following interleukin 23 (IL-23) stimulation. IL-17AF signals through the IL-17RA/IL-17RC receptor complex and functions to regulate inflammatory responses. IL-17AF induces chemokine and airway neutrophilia production, similar in function to IL-17A and IL-17F homodimers. In regard to these functions, IL-17AF is less active than the IL-17A homodimer and shows greater activity than the IL-17F homodimer. Human and rat IL-17AF are active on mouse cells. |
Size | 5ug, 25ug, 100ug, 500ug, 1mg |
Concentration | n/a |
Applications | Bioactive |
Other Names | IL17, IL17A, CTLA-8, IL-17A, CTLA8, IL-17, IL17F, IL-17F, IL-17F, ML-1, ML1, CANDF6 |
Gene, Accession, CAS # | IL17, Gene ID: 16171; 257630, UniProt: Q62386; Q7TNI7 |
Catalog # | QP5205-5ug |
Price | |
Order / More Info | Recombinant Mouse IL-17AF Protein from ENQUIRE BIOREAGENTS |
Product Specific References | n/a |
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