产品详情 |
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Antigenic Specificity | GALE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100µg |
Concentration | n/a |
Applications | ELISA, WB, IHC • WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:10 - 1:100 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-GALE polyclonal antibody. This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardatio |
Immunogen | UDP-galactose-4-epimerase |
Other Names | n/a |
Gene, Accession # | Gene ID: 2582, UniProt: Q14376 |
Catalog # | FNab03309 |
Price | |
Order / More Info | GALE Antibody from FINETEST |
Product Specific References | n/a |
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