产品详情 |
Edit |   |
Antigenic Specificity | GLUD1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100µg |
Concentration | n/a |
Applications | ELISA, WB, IHC, IP • WB 1:500 - 1:2000; IHC 1:100 - 1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-GLUD1 polyclonal antibody. This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosom |
Immunogen | glutamate dehydrogenase 1 |
Other Names | GLUD |
Gene, Accession # | Gene ID: 2746, UniProt: P00367 |
Catalog # | FNab03498 |
Price | |
Order / More Info | GLUD1 Antibody from FINETEST |
Product Specific References | n/a |
产品资料 |
|
|