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| Antigenic Specificity | Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (aa 700-800) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat, mouse |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).Subcellular location: Membrane, Multi-pass membrane protein.Tissue specificity: Expressed in pancreatic islets and in brain, where it has been seen in hippocampus, basal ganglia, habenula and thalamus. No expression in skeletal muscle. Also known as: Voltage-dependent L-type calcium channel subunit alpha-1D, Voltage-gated calcium channel subunit alpha Cav1.3, Calcium channel, L type, alpha-1 polypeptide, CACH3, CACN4, CACNL1A2, CCHL1A2, Cav3.1. |
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| Immunogen | A synthetic peptide from aa region 700-800 of human CACNA1D (Cav1.3) conjugated to an immunogenic carrier protein was used as the antigen. |
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| Other Names | cacna1d|cav1.3a|isl|si:dz136d19.3|si:dz223c6.1|ca(v)1.3|cav1.3|CACH3|CACN4|CACNL1A2|CCHL1A2|Cav1.3|SANDD|8430418G19Rik|C79217|Cacnl1a2|Cchl1a|Cchl1a2|D-LTCC |
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| Gene, Accession # | Gene ID: 776,12289,29716 |
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| Catalog # | ABIN350139 |
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| Order / More Info | Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D) (aa 700-800) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 7553731, 17081983, 1309948, 1309651, 7557998 |
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