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| Product Name | CD11b, Recombinant, Human, aa936-1154 |
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| Description | Highly Purified (~95%). Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (aMb2) molecule, also known as macrophage-1 antgen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A, and cluster of differentiation molecule 11B (CD11B). The second chain of aMb2 is the common integrin beta2 subunit known as CD18, and integrin aMb2 thus belongs to the beta2 subfamily (or leukocyte) integrins. aMb2 is expressed on the surface of many leukocytes involved in the innate immune system, including monocytes, granulocytes, macrophages, and natural killer cells. It mediates inflammation by regulating leukocyte adhesion and migration and has been implicated in several immune processes such as phagocytosis, cell-mediated cytotoxicity, chemotaxis and cellular activation. It is involved in the complement system due to its capacity to bind inactivated complement component 3b (iC3b). The ITGAM (alpha) subunit of integrin aMb2 is directly invo |
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| Size | 2ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | CD11b, Recombinant, Human, aa936-1154 (ITGAM, Integrin alpha M, Mac-1, Macrophage-1 antigen, Complement receptor 3, CR3, CR3A, Cluster of Differentiation Molecule 11B) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208774 |
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| Order / More Info | CD11b, Recombinant, Human, aa936-1154 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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