| 产品详情 |
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| Product Name | SHIP2 Inhibitor II, CPDA |
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| Description | Purity ~98% (HPLC). A cell-permeable aminopyridine acetamide based compound that acts as an inhibitor of SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) that can overcome insulin resistance in 3T3-L1 adipocytes. Enhances insulin-stimulated Akt phosphorylation (Thr308) in TNFa-treated 3T3-L1 adipocytes (~10uM) and in primary cultured neurons from rat cerebral cortex. Improves glucose tolerance in db/db mice (~300mg/kg b.i.d) without affecting their fasting glucose levels. Also reduces the expression levels of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase. Primary Target: SHIP2 Solubility: DMSO |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217789 |
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| Order / More Info | SHIP2 Inhibitor II, CPDA from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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