| 产品详情 |
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| Antigenic Specificity | PUF60 |
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| Clone | GT3510 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PUF60 Monoclonal Antibody (GT3510). PUF60 encodes a protein that is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene. |
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| Immunogen | n/a |
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| Other Names | SIAHBP1, FIR, poly-U binding splicing factor 60KDa, RoBPI |
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| Gene, Accession # | Entrez: 22827, 67959, 84401; Uniprot: Q3UEB3, Q9UHX1, Q9WV25 |
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| Catalog # | MA5-27821 |
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| Price | |
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| Order / More Info | PUF60 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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