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| Product Name | Interferon-y, Mouse, BioAssay™ ELISA Kit (IFN-y) |
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| Description | IFN- is a multifunctional cytokine, possessing important immune-modulation, anti-viral and anti-tumor properties. It is produced by natural killer cells and natural killer T cells, plays an important part in innate immunity. CD4+ T helper 1 cells, CD8 cytotoxic T lymphocyte (CTL) and effecter T cells also produce IFN-y when acquired immunity develops. IFN- stimulates its own expression and up-regulates other genes through the Jak-Stat signaling pathway. IFN-y released after viral infection stimulates the production of large amount of protein kinase R, which phosphorylates transcription initiation factor elF in response to viral infection. As a results, enzymes critical to mRNA replication is reduced and mRNA replication inhibited. Experiment with murine cytomegalovirus infected mice (1) showed that natural killer cells are the main source of IFN-y. In natural killer cell depleted mice, viral hepatitis and viral replication levels were higher than control group. The experiment also de |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 216003 |
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| Order / More Info | Interferon-y, Mouse, BioAssay™ ELISA Kit (IFN-y) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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