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| Product Name | Interleukin-8, active (CXCL8), Recombinant, Human |
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| Description | Purity ≥97% as determined by SDS-PAGE and HPLC. IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (ECO:0000269|PubMed:11978786, ECO:0000269|PubMed:2145175, ECO:0000269|PubMed:2212672). Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human CXCR2 transfected mouse BaF3 cells is less than 2ng/ml, corresponding to a specific activity of 5.0 x10e5 IU/mg. |
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| Size | 5ug, 25ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-8, Chemokine C-X-C motif, ligand 8, Emoctakin, Granulocyte chemotactic protein 1 |
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| Gene, Accession, CAS # | IL8_HUMAN, SwissProt: P10145 |
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| Catalog # | 348153 |
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| Order / More Info | Interleukin-8, active (CXCL8), Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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