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| Product Name | Transferrin, Rat, Western Blot Positive Control (Tf) |
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| Description | Purity > 95%. Elemental iron is required for a variety of normal cellular functions and vital for proper growth and development. However, natural iron is quite insoluble and excess iron is harmful, since it can catalyze the formation of potentially damaging reactive oxygen species. The major pool of body iron (~85%; 40-50 mg/kg) is found in circulating hemoglobin and muscle myoglobin. Iron absorption occurs primarily in the intestine (duodenum) and inversely related to body iron reserve. Several proteins including Ferritin, transferrin (Tf), transferrin receptors (TfRs), and iron regulatory proteins (IRPs) etc play a key role in iron metabolism. Transferrin (Tf, human chromosome 3, 679 aa), a serum glycoprotein of ~80kD and synthesized in the liver, is the primary protein of inter-organ transport of nonheme iron. Tf can bind two iron atoms. Tf binds to membrane Transferrin receptors (TfRs) and taken up by endocytosis. Iron is released from Tf, within acidic endosomes, into the cytoplas |
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| Size | 100ul |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | Transferin, TF, Apotransferrin, Beta-1 Metal-binding Globulin, DKFZp781D0156, PRO1400, PRO1557, PRO2086, Serotransferrin Precursor, Siderophilin |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T8199-06 |
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| Order / More Info | Transferrin, Rat, Western Blot Positive Control (Tf) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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