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| Product Name | Transferrin Receptor, Soluble, Recombinant |
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| Description | Purity ≥95% (SDS-PAGE). The transferrin receptor (TfR) is the gateway for transferrin-bound-iron entering all body cells. TfR is abundant on the surface of many newly formed cells, but the erythroid narrow cells account for 70 to 80% of the total body TfR content. The soluble (or serum) transferrin receptor (sTfR) is a circulating truncated form of the membrane receptor protein; it is an 85kD glycoprotein forming in serum a 320kD complex with diferric transferrin. The serum sTfR concentration reflects the total body mass of cellular transferrin receptor. Anemias associated with enhanced erythropoiesis and iron deficiency result in an elevation in the sTfR values. The normal sTfR concentrations are about 0.8-2.3ug/ml for adults, the iron deficiency may increase the values up to 20 fold. Elevation of the soluble transferrin receptor may be also caused by hemolytic anaemia, polycythemia and thalassemia while aplastic anemia and chronic renal failure may result in decrease. The most important clinical use of the |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 474332 |
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| Order / More Info | Transferrin Receptor, Soluble, Recombinant from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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