| 产品详情 |
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| Product Name | PIK-III |
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| Description | Purity >98%. PIK-III is an inhibitor of the type 3 phosphatidylinositol 3-kinase (PI3K) vacuolar protein sorting 34 (Vps34) that binds a unique hydrophobic pocket (IC50 = 18 nM). It is selective for Vps34 over related PI3K isoforms, PI4KBeta, and mTOR. PIK-III acutely inhibits autophagy and de novo lipidation of LC3, leading to stabilization of autophagy substrates. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4'-(cyclopropylmethyl)-N2 -4-pyridinyl-[4,5'-bipyrimidine]-2,2'-diamine, Vacuolar Protein Sorting 34 Inhibitor 2, Vps34 Inhibitor 2, Vps34-IN2 |
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| Gene, Accession, CAS # | CAS: 1383716-40-2 |
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| Catalog # | LS-H9415 |
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| Price | |
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| Order / More Info | PIK-III from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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