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| Product Name | PI3K, p110 delta, p85 alpha, Recombinant, Human, His-Tag (Phosphoinositide 3 Kinase) |
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| Description | Purified (~70-90%). PI3K (p110d/p85a) is a member of the PI3K family that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. PI3K (p110d/p85a) plays a role in oncogenic transformation, and is consistently expressed at a high level in blast cells from AML. PI3K (p110d/p85a) can play a selective role in the amplification of phosphatidylinositol (3,4,5) trisphosphate (PIP3) levels that lead to neutrophil polarization, and regulates directional migration, but not random locomotion. PI3K (p110d/p85a) signaling pathway is involved in immune responses relevant to the pathogenesis of rheumatoid arthritis and other inflammatory diseases. Source: Recombinant protein corresponding to human PI3K, fused to His-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~86kD, 111kD Specific Activity: 50nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_005026 |
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| Catalog # | 500365 |
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| Order / More Info | PI3K, p110 delta, p85 alpha, Recombinant, Human, His-Tag (Phosphoinositide 3 Kinase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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