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| Product Name | Recombinant Human Transcription termination factor 1 |
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| Description | 11-242aa; Partial. MW: 29.7kD. Purity >90% as determined by SDS-PAGE. Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity. |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [RNA polymerase I termination factor; Transcription termination factor I; TTF-I] |
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| Gene, Accession, CAS # | TTF1, Gene ID: 7270, Accession: NP_001192225.1 |
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| Catalog # | MBS1265310 |
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| Order / More Info | Recombinant Human Transcription termination factor 1 from MYBIOSOURCE INC. |
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| Product Specific References | Molecular evolution of mammalian ribosomal gene terminator sequences and the transcription termination factor TTF-1.Evers R., Grummt I.Proc. Natl. Acad. Sci. U.S.A. 92:5827-5831(1995) DNA sequence and analysis of human chromosome 9.Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L., Bailey J., Banerjee R., Barker D.J |
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