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Product Name | Nutlin 3a |
Description | MDM2 antagonist (IC50 = 90 nM); inhibits the MDM2-p53 interaction. Active enantiomer of Nutlin-3 (Cat. No. 3984). Induces expression for P53 regulated genes. Suppresses tumor growth in vivo >98% in prostate cancer and osteosarcoma cancer models. Antiproliferative. Purity 97%. MW (observed): 581.49 |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone |
Gene, Accession, CAS # | CAS: 675576-98-4 |
Catalog # | 6075/5 |
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Order / More Info | Nutlin 3a from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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