| 产品详情 |
| Edit |   |
|---|
| Product Name | Diubiquitin (DUB) K48-linked Substrates (Deconjugating Enzyme FRET), BioAssay™ Kit |
|---|
| Description | Linkage specific diubiquitin (DUB) is a substrate for enzymes that cleave the isopeptide linkage between two ubiquitin molecules. These FRET-based DUB substrates with isopeptide bonds between ubiquitin moieties are superior to gel densitometry assays. Since DUBs recognize and cleave substrates with specific steric conditions, each substrate varies in the position of the fluorophore and quencher and must be empirically tested for individual enzymes. These fluor-based substrates are superior to current stop time gel densitometry assays which are not scalable and are time and substrate consuming. However, DUB substrate specificity is influenced by many parameters and variables. These include but are not limited to: isopeptide linkages, fluor labels, tags and label/tag positions. Due to these variables, there is no universal diubiquitin substrate for all DUBs and variables must be optimized for each DUB. Each substrate in this kit varies in the position of the fluorophore and quencher and |
|---|
| Size | 1 kit |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | D3783-10 |
|---|
| Price | |
|---|
| Order / More Info | Diubiquitin (DUB) K48-linked Substrates (Deconjugating Enzyme FRET), BioAssay™ Kit from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|