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| Product Name | ZIPK, Control Peptide (ZIPtide, Zip Kinase) |
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| Description | Purity ~ 90%. Synthetic substrate peptide (KKLNRTLSFAEP-G) (linear) for ZIPK. Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. Applications: Analytical Tests: Peptide identity confirmed by MALDI-ToF MS and Amino Acid analysis. Kinase Assay: Substrate for ZIPK, active. |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | Z0550-01A |
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| Order / More Info | ZIPK, Control Peptide (ZIPtide, Zip Kinase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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