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| Product Name | FMS, Recombinant, Human, GST-Tag (CSF1R, CSFR, FIM2, C-FMS, CD115) |
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| Description | Purified (~70-90%). FMS is a proto-oncogene that encodes the tyrosine kinase transmembrane receptor for colony stimulating factor 1 (CSF1). FMS is homodimeric that contains a so-called kinase insert domain and is a member of the CSF1/PDGF receptor family of tyrosine-protein kinases. FMS mediates most if not all of the biological effects of CSF1 which control the production, differentiation, and function of cell of the monocyte/macrophage lineage. Mutations in FMS have been associated with providing sustained signals for cell growth and a predisposition to myeloid malignancy. Source: Recombinant protein corresponding to human FMS fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~76kD Specific Activity: 24nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_005211 |
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| Catalog # | 500021 |
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| Order / More Info | FMS, Recombinant, Human, GST-Tag (CSF1R, CSFR, FIM2, C-FMS, CD115) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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