产品详情 |
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Product Name | Vaborbactam |
Description | A β-lactamase inhibitor (Kis = 29-110 nM for class A and class C enzymes); selective for bacterial β-lactamases over a panel of mammalian serine proteases (IC50s = ≥1,000 µM); potentiates the activity of biapenem against K. pneumonia expressing KPC-2 at 0.02 µg/ml; potentiates the activity of carbapenem antibiotics against clinical isolates of various bacteria (MICs = ≤0.06-4 and 4-64 µg/ml in the presence and absence of compound, respectively); reduces the number of CFUs in the lung in a neutropenic mouse lung infection model when used in combination with biapenem or meropenem at 50 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | RPX 7009 |
Gene, Accession, CAS # | CAS: 1360457-46-0 |
Catalog # | 23962-10 |
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Order / More Info | Vaborbactam from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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