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| Product Name | 5-fluoro 203 |
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| Description | Purity >98%. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. 5-fluoro 203 is a cytotoxic compound that at 1 µM activates AhR signaling, inducing transcription of CYP1A1, which leads to the formation of DNA adducts and cell cycle arrest. In certain ovarian, breast, kidney, and colorectal cancer cells, 5-fluoro 203 can increase the levels of reactive oxygen species as well as activate JNK, ERK, and p38 MAPK. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-(5-fluoro-2-benzothiazolyl)-2-methyl-benzenamine, 5F-203, NSC 703786 |
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| Gene, Accession, CAS # | CAS: 260443-89-8 |
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| Catalog # | LS-H6212 |
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| Order / More Info | 5-fluoro 203 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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