| 产品详情 |
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| Product Name | 4-hydroxy Nonenal Glutathione-d3 (trifluoroacetate salt) |
| Description | Purity >99%. 4-hydroxy Nonenal Glutathione-d3 (4-HNE-GSH-d3 (trifluoroacetate salt) contains three deuterium atoms at the terminal methyl position. It is intended for use as an internal standard for the quantification of 4-HNE-GSH (trifluoroacetate salt) by GC- or LC-mass spectrometry. 4-hydroxy-Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ?-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid. 4-HNE-GSH is a major adduct formed by the reaction of 4-HNE with GSH. 4-HNE-GSH levels in liver, plasma, or isolated cells can serve as biomarkers for oxidative stress. The trapping of 4-HNE by glutathione to give HNE-GSH prevents the formation of DNA adducts with 4-HNE. In human polymorphonuclear leukocytes, HNE-GSH is metabolized to 1,4-dihydroxynonene glutathione (DHN-GSH), 4-hydroxynonenoic acid glutathione (HNA-GSH), and 4-hydroxy nonenal mercapturic acid (HNE-MA). |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | L-y-glutamyl-S-[(3S)-tetrahydro-5-hydroxy-2-pentyl-3-furanyl]-L-cysteinyl-glycine-11,11,11-d3 , trifluoroacetate salt, 4-HNE-GSH-d3 |
| Gene, Accession, CAS # | n/a |
| Catalog # | LS-H6127 |
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| Order / More Info | 4-hydroxy Nonenal Glutathione-d3 (trifluoroacetate salt) from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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