产品名称 Okadaic acid from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H12056
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameOkadaic acid
DescriptionPurity >98% by HPLC. Potent inhibitor of protein phosphatase 1 (IC50 = 3 nM) and protein phosphatase 2A (IC50 = 0.2-1 nM). Displays > 100,000,000-fold selectivity over PP2B and PP2C. Tumour promotor agent. Activates atypical protein kinase C in adipocytes. Induces JNK activation, bim overexpression and mitochondrial dysfunction in cultured rat cortical neurons.
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Other Names(2R)-3-[(2S,6R,8S,11R)-2-[(E,2R)-4-[(2S,2'R,4R,6R,8aR)-4-hydroxy-2-[(1S,3S)-1-hydroxy-3-[(3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[2,3-e]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-11-hydroxy-4-
Gene, Accession, CAS #CAS: 78111-17-8
Catalog #LS-H12056
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Order / More InfoOkadaic acid from LIFESPAN BIOSCIENCES INC.
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