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| Product Name | S100 Calcium Binding Protein A1-like, Recombinant, Human, aa1-147, His-Tag (S100A1L, S100AL, SNTN) |
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| Description | Purity ~90% (SDS-PAGE). SNTN, also known as sentan, belongs to the S-100 family. SNTN is shown to localize exclusively to the bridging structure between the cell membrane and peripheral singlet microtubules, which specifically exists in the narrowed distal portion of cilia. Exogenously expressed sentan showed affinity for the membrane protrusions, and a protein-lipid binding assay revealed that sentan bound to phosphatidylserine. These findings suggest that sentan is the first molecular component of the ciliary tip to bridge the cell membrane and peripheral singlet microtubules, making the distal portion of the cilia narrow and stiff to allow for better airway clearance or ovum transport. Source: Recombinant corresponding to aa1-147 from human SNTN, fused to His-tag at N-terminus expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MGGCMHSTQD KSLHLEGDPN PSAAPTSTCA PRKMPKRISI SKQLASVKAL RKCSDLEKAI ATTALIFRNS SDSDGKLEKA IAKDLLQTQF RNFAEGQETK PKYREILSEL DEHTENKLDF EDFMILLLSI TVMSDLLQNI |
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| Size | 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001074006 |
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| Catalog # | S0051-80Z |
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| Order / More Info | S100 Calcium Binding Protein A1-like, Recombinant, Human, aa1-147, His-Tag (S100A1L, S100AL, SNTN) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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