| 产品详情 |
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| Product Name | S100 Calcium Binding Protein A13, Recombinant, Mouse (S100A13) |
| Description | Purity > 97%, as determined by SDS-PAGE and visualized by silver stain. Mouse S100A13 is an 11kD member of the S100 (soluble in 100% saturated ammonium sulfate) family of vertebrate EF-hand Ca ++ -binding proteins. It is widely expressed as a homodimer with 98 amino acid (aa) long subunits. Mouse S100A13 shares 87%, 83%, 91%, 86%, 81% and 53% aa identity with rat, human, cow, dog, opossum and chicken S100A13, respectively. Like other S100 proteins, S100A13 is small and generally acidic, but it contains a basic residue-rich sequence at the C terminus, and two EF hand motifs that bind Ca++ with differing affinities. Some S100 proteins, including S100A13, are able to bind the cell surface receptor for advanced glycation end-products (RAGE). Despite lacking a signal sequence, S100A13 plays an important role in Cu ++ -dependent export of FGF-1 (FGF acidic) and IL-1 alpha from the cell in response to stresses such as heat shock, anoxia and starvation. Binding of copper is necessary for forma |
| Size | 50ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | Accession: NP_033139 |
| Catalog # | S0052-17K1 |
| Price | |
| Order / More Info | S100 Calcium Binding Protein A13, Recombinant, Mouse (S100A13) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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