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| Product Name | Recombinant Human Receptor-interacting serine/threonine-protein kinase 3 |
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| Description | 1-518aa; Full Length. MW: 58.89kD. Purity >90% as determined by SDS-PAGE. Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosph |
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| Size | 0.01 mg (Yeast), 0.05 mg (Yeast), 0.01 mg (Baculovirus), 0.1 mg (Yeast), 0.02 mg (Baculovirus) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3] |
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| Gene, Accession, CAS # | RIPK3, Gene ID: 11035, Accession: NP_006862.2 |
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| Catalog # | MBS1442585 |
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| Order / More Info | Recombinant Human Receptor-interacting serine/threonine-protein kinase 3 from MYBIOSOURCE INC. |
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| Product Specific References | Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB.Yu P.W., Huang B.C.B., Shen M., Quast J., Chan E., Xu X., Nolan G.P., Payan D.G., Luo Y.Curr. Biol. 9:539-542(1999) |
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