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| Product Name | Recombinant Human Receptor-type tyrosine-protein phosphatase beta |
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| Description | 1643-1997aa; Cytoplasmic Domain. MW: 57.36kD. Purity >90% as determined by SDS-PAGE. Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, wh |
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| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Vascular endothelial protein tyrosine phosphatase; VE-PTP] |
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| Gene, Accession, CAS # | PTPRB, Gene ID: 5787, Accession: NP_001103224.1 |
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| Catalog # | MBS962078 |
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| Order / More Info | Recombinant Human Receptor-type tyrosine-protein phosphatase beta from MYBIOSOURCE INC. |
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| Product Specific References | Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.Krueger N.X., Streuli M., Saito H.EMBO J. 9:3241-3252(1990) The full-ORF clone resource of the German cDNA consortium.Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.BMC Genomics 8:399-399(2007) The finished DNA sequence of hu |
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