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| Product Name | Recombinant Human Receptor-type tyrosine-protein phosphatase C |
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| Description | 24-575aa; Extracellular Domain. MW: 62.78kD. Purity >90% as determined by SDS-PAGE. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one ses to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN |
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| Size | 0.01 mg (Yeast), 0.05 mg (Yeast), 0.1 mg (Yeast), 0.2 mg (Yeast), 0.5 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Leukocyte common antigen; L-CAT200; CD45] |
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| Gene, Accession, CAS # | PTPRC, Gene ID: 5788, Accession: NP_002829.3 |
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| Catalog # | MBS718210 |
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| Order / More Info | Recombinant Human Receptor-type tyrosine-protein phosphatase C from MYBIOSOURCE INC. |
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| Product Specific References | Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.Streuli M., Hall L.R., Saga Y., Schlossman S.F., Saito H.J. Exp. Med. 166:1548-1566(1987) Structural variants of human T200 glycoprotein (leukocyte-common antigen).Ralph S.J., Thomas M.L., Morton C.C., Trowbridge I.S.EMBO J. 6:1251-1257(1987) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., W |
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