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| Product Name | GMFB, Recombinant, Human (Glia Maturation Factor beta, GMF-beta) |
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| Description | Purity ~98% (SDS-PAGE, HPLC). Glia Maturation Factor-Beta (GMF-Beta) is a 17kD protein nerve growth factor identified as a growth and differentiation factor in the vertebrate brain. Glia Maturation Factor-Beta stimulates differentiation of normal neurons as well as glial cells. GMFB inhibits the proliferation of the N-18 neuroblastoma line and the C6 glioma line while promoting their phenotypic expression. GMF-beta enhances the phenotypic expression of glia & neurons thus inhibits the proliferation of their respective tumors when added to cell culture. Cell- surface GMF-Beta acts on the target cells at close range when cells are in direct contact. GMF-Beta is produced by thymic epithelial cells and plays an important role in T cell development in favor of CD4+ T cells. Source: Recombinant corresponding to human GMF-Beta expressed in E. coli. AA Sequence: SESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKRLVVLDEELEGISPDELKELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLTEEWLR |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P60983 |
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| Catalog # | G2035-65E |
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| Order / More Info | GMFB, Recombinant, Human (Glia Maturation Factor beta, GMF-beta) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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