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| Product Name | Omi, HtrA2, Recombinant, Human (HtrA serine peptidase 2) |
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| Description | Purity ≥ 90% Determined by Analysis by RP-HPLC. or reducing and non-reducing SDS-PAGE Coomassie. HtrA2 also called Omi is a mammalian serine protease at high temperatures and has a chaperone activity at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP)-binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death. Recombinant Human HtrA2 amino acids 134-458 His-Tag fusion proein produced in E.Coli is a single,non-glycosylated polypeptide chain having a molecular mass of 32kD. Sequence: MAVPSPPPAS PPSQYNFIAD VVEKTAPAVV YIEILDRHPF LGREVPISNG SGFVVAADGL IVTNAHVVAD RRRVRVRLLS GDTYEAVVTA VDPVADIATL RIQTKEPLPT LPLGRSADVR QGEFVVAMGS PFALQNTITS |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | O6350-10 |
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| Order / More Info | Omi, HtrA2, Recombinant, Human (HtrA serine peptidase 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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