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| Product Name | XRCC4, Recombinant, Human, aa1-336, GST-Tag (DNA Repair Protein XRCC4) |
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| Description | Purity ~90% (SDS-PAGE). Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. Source: Recombinant protein corresponding to aa1-336 from human XRCC4, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~65.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | X-ray repair cross-complementing protein 4 |
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| Gene, Accession, CAS # | SwissProt: Q13426 |
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| Catalog # | 375883 |
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| Order / More Info | XRCC4, Recombinant, Human, aa1-336, GST-Tag (DNA Repair Protein XRCC4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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