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| Product Name | MEKK6, Recombinant, Human, GST-Tag (Mitogen-Activated Protein Kinase Kinase Kinase 6, MAP3K6, MAPKKK6, ASK2) |
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| Description | Purified (~70-90%). MEKK6 or MAP3K6 (mitogen-activated protein kinase kinase kinase 6) is a member of the serine/threonine protein kinase family. MEKK6 was identified by its interaction with MAP3K5/ASK, a protein kinase and an activator of c-Jun kinase (MAPK7/JNK) and MAPK14/p38 kinase. MEKK6 cascades relay signals from the cell surface to the nucleus which result in gene transcription. MEKK6 activates the JNK and p38 pathway and induces apoptosis when overexpressed in stably transfected cells. MEKK6 transcript is expressed in several tissues, with the highest expression in heart and skeletal muscle. Source: Recombinant protein corresponding to human MEKK6, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~67kD Specific Activity: 10nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_004672 |
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| Catalog # | 500251 |
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| Order / More Info | MEKK6, Recombinant, Human, GST-Tag (Mitogen-Activated Protein Kinase Kinase Kinase 6, MAP3K6, MAPKKK6, ASK2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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