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| Product Name | MEK1, Recombinant, Mouse, GST-Tag (EE, MAP2K1, MKK1, MAPKK1, PRKMK1) |
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| Description | Purified (~70-90%). MEK1 (EE) is a member of the dual specificity protein kinase family that acts as a mitogen-activated protein kinase (MAPK) kinase. MEK1 lies upstream of MAPK/ERK and stimulates the enzymatic activity of MAPK/ERK upon a wide variety of extra- and intracellular signals. As an essential component of MAPK/ERK signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. Constitutive activation of MEK1 results in cellular transformation. Thus, MEK1 represents a likely target for pharmacologic intervention in proliferative disease such as cancer. Source: Recombinant protein corresponding to mouse MEK1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~69kD Specific Activity: 326nmol/min/mg as per activity assay protocol. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_008927 |
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| Catalog # | 500244 |
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| Order / More Info | MEK1, Recombinant, Mouse, GST-Tag (EE, MAP2K1, MKK1, MAPKK1, PRKMK1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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