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| Product Name | Liproxstatin-1 |
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| Description | A ferroptosis inhibitor; inhibits ferroptotic cell death (IC50 = 22 nM) and lipid peroxidation in inducible Gpx4-/- MEFs at 50 nM; inhibits ferroptosis induced by the ferroptosis-inducing agents BSO, erastin, and (1S,3R)-RSL3 in a concentration-dependent manner in MEFs; inhibits cell death and lipid peroxidation induced by (1S,3R)-RSL3 in human renal proximal tubule epithelial cells; increases survival and decreases TUNEL+ kidney cells in inducible Gpx4-/- mice at 10 mg/kg; reduces tissue injury in a mouse model of hepatic ischemia/reperfusion injury; an antioxidant that inhibits autooxidation of lipids by trapping peroxyl radicals |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ferroptosis Gpx-4 auto-oxidation anti-oxidant |
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| Gene, Accession, CAS # | CAS: 950455-15-9 |
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| Catalog # | 17730-25 |
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| Order / More Info | Liproxstatin-1 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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