| 产品详情 |
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| Product Name | ABX-1431 |
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| Description | An inhibitor of MAGL (IC50s = 14 and 27 nM for human and rat enzyme, respectively); selective for MAGL over ABHD6 and PLA2G7 (IC50s = 2.7 and >10 µM, respectively), as well as a panel of 33 serine hydrolases and a panel of 95 enzymes, receptors, transporters, and ion channels at 10 µM; selective for MAGL over CYP1A2, CYP2C9, CYP2C19, and CYP3A4/5 (IC50s = >50 µM); inhibits MAGL activity in mouse and rat brain ex vivo (ED50s = 1.4 and 0.5 mg/kg, respectively); decreases brain levels of 2-AG in mice and rats; reduces formalin-induced paw-licking time in rats |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 1446817-84-0 |
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| Catalog # | 26023-1 |
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| Price | |
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| Order / More Info | ABX-1431 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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