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| Product Name | Aldo-Keto Reductase Family 1 Member C3, aa1-323, Human, His-Tag, Recombinant |
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| Description | Purity ~95% (SDS-PAGE) Endotoxin: <1.0EU/ug of protein (LAL). AKR1C3, also known as PGFS, is a member of the aldo-keto reductase superfamily which catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9 alpha, 11 beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and differentiation. Recombinant human AKR1C3 protein, fused to His-tag at N-terminus, expressed in E.coli. Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD IVDLCTTWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNRS KLLDFCKSKD IVLVAYSALG SQRDKRWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ L |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Aldo-Keto Reductase Family 1 Member C3, aa1-323, Human, His-Tag, Recombinant (AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, KIAA0119) |
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| Gene, Accession, CAS # | Accession: NP_003730 |
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| Catalog # | A1334-70P |
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| Order / More Info | Aldo-Keto Reductase Family 1 Member C3, aa1-323, Human, His-Tag, Recombinant from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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