| 产品详情 |
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| Product Name | Aldo-keto Reductase Family 1 Member C1, Recombinant, Human |
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| Description | Purity ~90% (SDS-PAGE). AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. Recombinant protein corresponding to aa1-323 of human AKR1C1 6x His tagged expressed in E. coli. Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MDSKYQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEATKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWCNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV SVKPGEEVIP KDENGKILFD TVDLCATWEA VEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEPWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTS EEMKAIDGLN RNVRYLTLDI FAGPPNYPFS DEY Biological Activity: Specific activity is ~0.15-0. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | Aldo-keto Reductase Family 1 Member C1, Recombinant, Human (AKR1C1, 20-alpha-hydroxysteroid Dehydrogenase, 20-alpha-HSD, 2-alpha-HSD, C9, Chlordecone Reductase Homolog HAKRC, Indanol Dehydrogenase, Dihydrodiol Dehydrogenase 1/2, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, High-affinity Hepatic Bile Acid-binding Protein, HBAB, MBAB, MGC8954, Trans-1,2-dihydrobenzene-1,2-diol Dehydrogenase) |
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| Gene, Accession, CAS # | Accession: NP_001344 |
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| Catalog # | A1334-70L |
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| Order / More Info | Aldo-keto Reductase Family 1 Member C1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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