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| Product Name | Aldo-Keto Reductase Family 1 Member C4 , Recombinant, Human, aa1-323, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). AKR1C4 belongs to aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. It catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. Purified by using conventional chromatography. Source: Recombinant corresponding to aa1-323 of human AKR1C4, fused to His-tag at N-terminal, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MDPKYQRVEL NDGHFMPVLG FGTYAPPEVP RNRAVEVTKL AIEAGFRHID SAYLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWCTFF QPQMVQPALE SSLKKLQLDY VDLYLLHFPM ALKPGETPLP KDENGKVIFD TVDLSATWEV MEKCKDAGLA KSIGVSNFNC RQLEMILNKP GLKYKPVCNQ VECHPYLNQS KLLDFCKSKD IVLVAHSALG TQRHKLWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIREN IQVFEFQLTS EDMKVLDGLN RNYRYVVMDF LMDHPDYPFS DEY Molecular Weight: ~39.2kD (343aa), confirmed by MALDI-TOF Bio |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Aldo-Keto Reductase Family 1 Member C4 , Recombinant, Human, aa1-323, His-Tag (AKR1C4, HGNC:387, 3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581, 3-alpha Hydroxysteroid Dehydrogenase Type I, 3 alpha-Hydroxysteroid Dehydrogenase, 3-alpha-Hydroxysteroid Dehydrogenase Variant, Chlordecone Reductase, Dihydrodiol Dehydrogenase 4, Type I 3-alpha-Hydroxysteroid Dehydrogenase) |
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| Gene, Accession, CAS # | Accession: NP_001809 |
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| Catalog # | A1334-70Z |
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| Order / More Info | Aldo-Keto Reductase Family 1 Member C4 , Recombinant, Human, aa1-323, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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