产品详情 |
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Product Name | Pyrroloquinoline quinone |
Description | A quinone with diverse biological activities; inhibits fibril formation by Aβ42 and mouse prion protein at 100 and 300 µM; stimulates cell proliferation, reduces glutamate-induced production of ROS, necrosis, and caspase-3 activity and increases activity of SOD, CAT, and GPX in neural stem and progenitor cells; inhibits LPS-induced production of NO and PGE2 and suppresses LPS-induced expression of various pro-inflammatory mediators in primary microglia; reduces Iba-1 expression in the cerebral cortex and hippocampal dentate gyrus in mice at 3 and 10 mg/kg; decreases the number of α-SMA-positive hepatic cells, collagen deposition, and hepatic hydroxyproline levels in a mouse model of liver fibrosis; decreases serum glucose and total cholesterol levels, increases brain SOD, CAT, and GPX activities, and decreases brain lipid hydroperoxide levels in mice with streptozotocin-induced diabetes |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | PQQ |
Gene, Accession, CAS # | CAS: 72909-34-3 |
Catalog # | 20681-1 |
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Order / More Info | Pyrroloquinoline quinone from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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